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MEDIA BRIEFING


25th September 2008



Risky Business: New 10-Country Survey Suggests Adults 40 and Older
Often Live Dangerously, Even When They Say They Aren’t “Risk-Takers”


• Majority say they’re not health risk-takers, yet many skip critical health screenings or forget to take prescribed blood pressure and cholesterol medications
• Up to one-half may have elevated heart disease risk, yet significant numbers have not spoken with their physicians about low-dose Aspirin, recently cited as a life-saving preventive intervention by major health organizations


Morristown, N.J. (Sept. 22, 2008) — A new survey of adults 40 and older from 10 countries around the world reveals a significant gap between people’s perceptions that they play it safe with their health versus their practice of engaging in risky health behaviors. Surveys were conducted in Argentina, Canada, China, Germany, Italy, Japan, Mexico, South Korea, Spain, and the United States. Overall, nearly half or more respondents claim they do not take health risks, including those related to cardiovascular disease (CVD), the world’s number one killer. Interestingly, depending on the country, approximately one-fourth to nearly one-half of those surveyed were determined to be at elevated CVD risk.* Yet, in most of the countries surveyed, more than a fourth of those deemed to be at elevated CVD risk say they have not spoken to their physicians about the preventive benefits of low-dose Aspirin therapy; this was particularly pronounced in Japan, where a staggering 83 percent of those deemed to be elevated CVD risk had not spoken with their physicians about this recognized therapy. Also surprising, many respondents in each country admit to skipping routine mammograms or prostate cancer screenings, colonoscopies and other screenings after the age of 50, and not taking (regularly or at all) prescribed medications including blood pressure and cholesterol medications, even though many are careful to get regular or occasional checks of their blood pressure or cholesterol.

*Using respondent self reports on their personal health and a formula based in part on the Framingham Risk Calculator, a measurement tool that assesses an individual's risk profile using a series of factors, including age, gender, previous cardiovascular events, presence of risk factors such as high cholesterol, blood pressure or diabetes, and other contributors such as smoking and family history of heart disease.


Greater, appropriate use of preventive measures that include Aspirin therapy, weight loss, cholesterol and blood pressure reduction, and smoking cessation would reduce heart attacks by 36 percent over the next three decades, according to a report issued by the American Heart Association (AHA) and two other major health organizations and published in recent issues of Circulation(1) and Diabetes Care (2). In addition, the American Medical Association (AMA) in July passed policy to increase education among physicians on the importance of appropriate Aspirin counseling for the prevention of heart disease and stroke. Encouraging physicians to incorporate Aspirin counseling into patient care when appropriate, may help reduce the prevalence of heart disease and stroke, said the AMA.

The new survey results were released today in conjunction with the World Heart Federation’s World Heart Day 2008, a global advocacy campaign for increasing public awareness and promoting use of preventive measures to reduce the incidence of cardiovascular disease (CVD). World Heart Day 2008 will be observed on Sunday, 28 September. This year’s theme, “Know Your Risk,” focuses on improving understanding of personal risk for cardiovascular disease, including hypertension. As part of the campaign, heart health screening and other activities for the public are being planned in over 100 countries worldwide.

“On the occasion of World Heart Day, this survey shows there still is much work to be done when it comes to risk factor education, and encouraging behaviors that can reduce the risk of cardiovascular disease,” said Wes Cetnarowski, MD, Senior Vice President of Global Research and Development at Bayer HealthCare. “We hope this latest survey report – as well as the ongoing efforts of organizations such as the World Heart Federation, the AHA, the AMA, and other health organizations worldwide – encourages and increases discussion between physicians and appropriate patients regarding the importance of preventive lifestyle changes and proven risk-reduction therapies that include low-dose Aspirin therapy.”


Elevated Risk, Gaps in Knowledge
Across the 10 countries surveyed, significant proportions of respondents, from a low of 23 percent (S. Korea) to a high of 42 percent (United States), are at self-reported elevated risk for CVD. When survey percentages are extrapolated to total populations of men over 40 and women over 50 (mimicking the population screened for elevated risk in the survey), some alarming numbers result. For example, in the United States this could mean as many as 47.8 million people, in Germany 12.6 million, and in Japan 14.2 million could be at elevated risk for CVD.(3)

When it comes to knowledge about risk factors for heart attack and stroke, overall, across the 10 countries surveyed, respondents tend to rate themselves as somewhat to very knowledgeable. However, there are still major gaps. In most countries, more than one in five respondents say they are not knowledgeable about heart attack risk factors, and more than one in four do not feel they are knowledgeable about stroke risk. And, though most country respondents have high awareness (74 percent or better) of the benefits of Aspirin in protecting against a second heart attack or stroke, and/or its ability to help save a life if taken during a heart attack, disappointingly high numbers of those identified as having elevated CVD risk report they had never discussed Aspirin therapy with their physician or healthcare professional. This was true of more than one-third to nearly one half of those deemed to be at elevated CVD risk in countries such as South Korea, Spain, Germany and Italy; in Japan, the percentage was much higher, with 83 percent of those deemed to be at elevated risk not having had that discussion with their physician.

Health Risk-Takers Around the World - The Highs and Lows
While the complete survey report is available, following are some of the highs and lows when it comes to the world’s risk-takers in this survey:
• Respondents across the 10 countries generally believe they play it safe when it comes to their health, ranging from a high of 70 percent of South Korean respondents to a low of 23 percent of Japanese respondents.
• Routine mammograms or prostate screenings are skipped by approximately one-fourth to one-half of respondents. From 22 percent (Japan) to 36 percent (Italy) of those surveyed report skipping colonoscopies and other screenings after the age of 50.
• Reports of forgetting to take prescribed medications range from 17 percent in Germany to 50 percent in S. Korea. More specifically, as many as 39 percent of respondents in China and S. Korea say that they forget to take anti-hypertensive or cholesterol-lowering medications. Overall, from 12 to 39 percent of respondents admit to forgetfulness for these cardiovascular medications.
• From 22 percent (China) to 38 percent (Germany) of respondents smoke or use tobacco at least occasionally, even though a majority of those polled in 9 of 10 countries considered smoking or tobacco use to be a high-risk activity (the exception being China).
• Throughout the countries surveyed, routine influenza shots are often skipped, by as many as 53 percent of respondents in the US to 30 percent in Argentina.
• A majority of respondents from all countries report that they regularly or occasionally exercise with China, Mexico, South Korea, and Canada (80, 78, 75, and 75 percent respectively) being the most proactive.
• Outside of health, many survey respondents also say they recognize where the risks lie. Out of seven, non-health related behaviors, not wearing a seat belt and driving over the speed limit were clearly recognized as the riskiest of daily activities in nearly all countries but Canada and the US, where skydiving took the number one spot and speeding was ranked near the bottom of the risky behaviors list.

About the Survey Methodology
The research findings come from a 10-country global online panel survey project (conducted by GMI and sponsored by Bayer HealthCare) that included over 3,000 consumer respondents in North America, Latin America, Europe, and Asia (Argentina, Canada, China, Germany, Italy, Japan, Mexico, South Korea, Spain, and the United States). Findings in each country are based on approximately 300 respondents (male and female) per country 40 years of age or older.

About World Heart Day
Heart disease and stroke is the world’s No. 1 killer, claiming 17.5 million lives each year. That’s why World Heart Day was created, to increase public awareness of the risk of heart disease and stroke and to promote preventive measures. World Heart Day 2008 will be held Sunday, Sept. 28, 2008, with the theme, “Know Your Risk!” Activities run by World Heart Federation members and partners will include walks, runs, public talks, scientific forums, exhibitions, concerts, sporting events, and much more. For more details, visit www.worldheartday.com

About Aspirin
Aspirin, life-tested for generations, is one of the most extensively studied drugs in history and boasts extensive clinical experience; it has an enviable 110-year track record of efficacy and safety across a range of doses. More than 200,000 patients have been studied in more than 200 randomized clinical trials evaluating Aspirin efficacy and safety across a broad range of cardiovascular disease (CVD) indications. Aspirin is recognized as cornerstone therapy for reducing risk of (CVD) events, including, but not limited to, heart attack and ischemic stroke, based upon clinical studies and extensive clinical, real world, experience.

The cornerstone role of Aspirin continues to be supported and reinforced by the global scientific community, through multiple international and national medical guidelines recommending the use of low-dose Aspirin for prevention of CVD events in both the primary and secondary settings.
Aspirin, recognized worldwide as one of the most effective CVD therapies, is universally available and offers excellent value for its cost.

As with all drugs, Aspirin is not for everyone. The determination of who is an appropriate candidate for Aspirin therapy is a decision that must be made in consultation between doctor and patient. Patients should always talk with their physicians before starting or adjusting a low-dose Aspirin regimen.


References:

(1) Kahn R, Robertson RM, Smith R, Eddy D.  The impact of prevention on reducing the burden of cardiovascular disease.  Circulation 2008.  Published online before print 7 July 2008, doi: 10,1161. CIRCULATIONAHA.108.190186

(2)  Kahn R, Robertson RM, Smith R, Eddy D.  The impact of prevention on reducing the burden of cardiovascular disease.  Diabetes Care 2008;31:1-11.

(3)  Using population numbers for men over 40 and women over 50 from the US census bureau international database for each country representing 2007 numbers in the US, and 2000 numbers for Japan and Germany.  www.census.gov