Aspirin Foundation
Search
What is Aspirin?Uses of AspirinSuitabilityNews & EventsAbout the FoundationContact Us
  Home > Suitability
Suitability Mother and child



Using Aspirin Sensibly & Safely

Aspirin and Reye Syndrome


Position Papers




Suitability


What is Aspirin?

The chemical name of aspirin is acetylsalicylic acid, it was first produced in 1899 and has been in constant use as a pain and fever reliever ever since…it was also the world’s first anti-inflammatory drug

What Sort of Pains Can it Treat?
aspirin has been and continues to be used for all sorts of pains, including headache, migraine, sore throat, toothache, muscular pain, arthritis, neuralgia, period pain, and many of the symptoms associated with colds and flu.

How Does it Work to Reduce Pain?
aspirin works by reducing the sensitivity of the nerves both at the site of pain and in the central nervous system….paracetamol and ibuprofen work in a similar way as do the more powerful non-steroidal anti-inflammatory drugs

Is it Still Widely Used?
Certainly, the global consumption in the year 2000 was approximately 35000 tons, equivalent to about 100 billion tablets

What Else is it Used For?
Over the past 30 years it has become universally recognised as a very valuable treatment at low doses for the reduction of risk of heart disease and stroke and more recently there is increasing evidence that it can reduce the risk of some cancers and slow the development of Alzheimer’s disease

How Does it Work in Heart Disease?
aspirin, even in very small doses has a powerful effect on particles in our blood called platelets, and platelets are an important part of our blood clotting process….by reducing platelet stickiness aspirin is able to reduce the likelihood of platelets clumping together in our blood vessels which are the prime cause of heart attacks and ischaemic strokes

Wouldn’t it Cause Excessive Bleeding?
This is unlikely as there are many more clotting mechanisms in our blood that aspirin doesn’t affect….aspirin does just enough to have a beneficial effect and no more

What Side Effects Does it Have?
All drugs have side effects and of course aspirin is no exception, the most widely reported side effects are those related to the gastrointestinal tract and in some individuals aspirin can cause stomach bleeding and dyspepsia….it should also be used with caution in asthmatics as it could make this worse

Can Anything be Done to Reduce the Risk of Side Effects?
If a patient has asthma and is sensitive to aspirin, no amount of changing the formulation or reducing the dose will effect the adverse reaction….however for people who have some stomach upset with regular aspirin there are soluble or coated formulations which can reduce the effects

Anything Else I Should Know About Which People Shouldn’t Take it?
Yes, aspirin isn’t recommended in children because of its association with a condition called Reye’s Syndrome…..although a link between aspirin and Reye’s Syndrome hasn’t been firmly established, many countries around the world do restrict its use to individuals over 12 or in some instances 16 years

What is Reye’s Syndrome?
It’s a very rare but serious illness which seems to occur mainly in children who are suffering a viral infection such as chicken pox….very rarely such children will develop serious brain and liver problems which can be fatal and this was first noticed in the 1960s in Australia by a physician called Reye…..over the last 30 years or so it has been found that some children who have developed the Syndrome have also taken aspirin and this has lead to the general worldwide warning about the use of aspirin in children

Can Aspirin be Taken in Pregnancy?
Many medicines are not suitable to take during pregnancy, although you may have heard that aspirin is sometimes recommended for some pregnant women who have a condition called pre-eclampsia…however in this situation it is always prescribed by a doctor and if you are pregnant you should always consult a doctor before taking aspirin